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Table 1 Characteristics of participants

From: Correlation between time in range and serum uric acid in Chinese patients with type-2 diabetes: an observational cross-sectional study

Parameter

SUA Q1

SUA Q2

SUA Q3

SUA Q4

P

n

114

117

113

114

 

Male, n (%)

46 (40.35)

72 (62.54)

88 (78.57)

96 (84.21)

 < 0.001

Age (year)

58.72 ± 10.75

56.15 ± 11.59

52.21 ± 14.70#

51.27 ± 13.24#*

 < 0.001

Weight (kg)

65.11 ± 10.55

68.14 ± 12.17

73.02 ± 12.90#*

76.77 ± 12.34#*

 < 0.001

BMI (kg/m2)

24.05 ± 3.16

24.71 ± 3.66

25.35 ± 3.18#

26.32 ± 3.63#*

 < 0.001

Diabetes duration (year)

9.87 ± 7.89

8.99 ± 6.65

6.97 ± 6.75#

7.60 ± 7.82

0.005

Smokingn (%)

19 (16.96)

33 (29.73)

43 (40.95)

40 (38.83)

 < 0.001

SBP (mmHg)

134.18 ± 19.73

132.66 ± 15.57

135.29 ± 16.90

135.19 ± 18.73

0.547

DBP (mmHg)

78.58 ± 13.55

78.62 ± 9.20

80.95 ± 11.20

81.67 ± 13.31

0.261

SUA (µmol/L)

209.95 ± 33.66

281.43 ± 15.01#

341.90 ± 22.35#*

451.60 ± 65.34#*∆

 < 0.001

BUN (mmol/L)

5.28 ± 1.32

5.74 ± 1.33

5.58 ± 1.47

6.92 ± 4.88#*∆

 < 0.001

SCr (µmol/L)

49.50 ± 13.20

56.66 ± 16.25#

59.58 ± 15.30#

69.99 ± 19.44#*∆

 < 0.001

TC (mmol/L)

4.28 (3.47, 5.01)

4.47 (3.73, 5.09)

4.43 (3.72, 5.08)

4.47 (3.89, 5.34)

0.359

TG (mmol/L)

1.17 (0.81, 1.70)

1.43 (0.96, 1.80)

1.67 (1.23, 2.77)#*

2.00 (1.17, 3.03)#*

 < 0.001

HDL (mmol/L)

1.17 (1.00, 1.43)

1.10 (0.93, 1.31)#

0.99 (0.89, 1.14)#*

0.94 (0.84, 1.20)#*

 < 0.001

LDL (mmol/L)

2.60(1.96, 3.24)

2.80 (2.12, 3.41)

2.72 (2.15, 3.32)

2.74 (2.13, 3.29)

0.629

FBG (mmol/L)

7.94 ± 2.96

7.54 ± 2.81

7.69 ± 2.53

7.41 ± 2.67

0.425

HbA1c (%)

9.51 ± 2.22

9.25 ± 2.01

8.96 ± 2.24

8.27 ± 1.86#*

 < 0.001

TBR (%)

0.00 (0.00, 0.20)

0.00 (0.00, 0.00)

0.00 (0.00, 0.00)

0.00 (0.00, 0.00)

0.136

TIR (%)

63.35 (42.80, 83.07)

67.62 (37.93, 80.46)

67.27 (42.11, 83.69)

79.03 (59.89, 89.16)#*∆

 < 0.001

TAR (%)

34.97 (16.59, 56.81)

31.92 (18.38, 62.07)

30.47 (15.59, 57.89)

20.97 (10.19, 39.77)#*∆

 < 0.001

MAGE (mmol/L)

4.86 (3.94, 5.92)

4.85 (3.71, 6.11)

4.20 (3.28, 5.22)#*

3.58 (2.92, 4.82)#*

 < 0.001

SD (mmol/L)

2.54 (2.06, 3.45)

2.65 (1.97, 3.18)

2.16 (1.74, 2.73)#*

1.95 (1.45, 2.61)#*

 < 0.001

ADRR (mmol/L)

24.50 (17.96, 34.65)

24.37 (18.45, 36.93)

22.49 (15.20, 30.28)#*

18.39 (11.53, 27.01)#*

 < 0.001

MODD (mmol/L)

2.29 (1.82, 3.23)

2.27 (1.61, 3.06)

1.94 (1.41, 2.69)#

1.74 (1.10, 2.31)#*

 < 0.001

M value (mmol/L)

9.42 (4.23, 19.81)

8.36 (4.35, 18.42)

7.37 (3.12, 14.86)

4.29 (2.03, 11.13)#*

 < 0.001

Treatment, n (%)

    

0.574

 No treatment

95 (84.82)

93 (79.49)

88 (77.88)

94 (81.74)

 

 OHA

89 (79.46)

90 (76.92)

88 (77.88)

79 (68.70)

 

 Insulin

53 (47.32)

51 (43.59)

57 (50.44)

51 (44.35)

 

 OHA and insulin

48 (42.86)

41 (38.04)

52 (46.02)

44 (38.26)

 
  1. Normally distributed variables in the table are presented as the means ± SD, non-normally distributed values are presented as medians (25% and 75% interquartiles), and categorical variables are presented as frequencies (percentages). Student’s t-test was used for comparison of data with a normal distribution, Wilcoxon rank-sum test for those with abnormal distributions, and χ2 -test for categorical variables
  2. BMI body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, SUA serum uric acid, BUN blood urea nitrogen, SCr serum creatinine, TC total cholesterol, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein, FBG fasting blood glucose, HbA1c Hemoglobin A1C, TBR time below range, TIR time in range, TAR time above range, MAGE mean amplitude of glycemic excursions, SD standard deviation, ADRR average daily risk range, MODD mean of daily differences, OHA Oral hypoglycemic agents
  3. vs Q1 group, #P < 0.05
  4. vs Q2 group, *P < 0.05
  5. vs Q3 group, ∆P < 0.05
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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